This is also a good question to ask your healthcare provider, as results will vary. How much exercise does the trick? Experts say that any amount of exercise is good, but 30 minutes a day, five times a week of moderate intensity exercise has been shown to produce benefits. Paths to Mitigating Pain Naturallyįor chronic pain sufferers who are interested in naturally boosting endorphins, here are six suggestions:Įxercise: While primarily utilized for managing stress and maintaining a healthy weight, studies reveal that workouts also boost endorphin levels. Therefore, any patient concerned with reducing his or her dependence on opioids should have an interest in boosting endorphins as a meaningful, non-addictive addition to their pain management program. While the body is programmed to produce endorphins in response to pain, research shows that it actually produces fewer endorphins when given opioid painkillers – like codeine or morphine. The name comes from the combination of “endogenous” – meaning made by the body – and “morphine.” Which led to the branding of endorphins as natural painkillers. They’re released when the body encounters pain or stress, and their role is to inhibit the communication of pain signals. These molecules, called endorphins, are neuropeptides produced by the central nervous system and the pituitary gland. This was puzzling, until they realized that our bodies also make morphine-like molecules that bind to those same receptors. In the 70s and 80s, several groups of scientists discovered that our brains have specific receptors that bind opiates like morphine. There’s real science behind endorphins – the body’s natural painkillers. If this sounds too good to be true, it isn’t. This natural aide comes in the form of tiny molecules that help boost the body’s ability to block pain signals.
In the process, some are discovering an extra ally in the fight against pain.
ENDORPHIN RELEASE HOW TO
Non-narcotic approaches that range from treatments – like acupuncture, massage and electrotherapy – to practices like meditation and mindfulness are being put into action.Īs awareness and adoption for these treatments grow, patients are learning how to play a more proactive role in their own rehabilitation. In trazodone treated rats, brain β-endorphins were significantly higher on day 28 (929 ± 18.13 pg/g) compared with the levels measured on day 1 and day 9 of treatment (P = 0.001 both), showing slightly higher values than in control rats, yet without statistical significance (P = 0.137).In the current climate of the opioid epidemic, many are looking for drug-free alternatives to aid in the fight against chronic pain. Statistical significance was also recorded by comparison of the lower data obtained on day 9 of treatment (433.65 ± 14.67 pg/g) and those observed in the control group (P = 0.001).
Data on brain β-endorphin concentration showed a significant decrease on day 1 of trazodone administration (431.03 ± 11.57 pg/g) compared to data obtained from control rat brains (873.5 ± 18.32 pg/g P = 0.001). Endorphin concentrations recorded on day 28 (38.62 ± 1.42 pg/mL) were higher compared to those measured on day 9 (P = 0.439). However, trazodone produced significantly lower β-endorphin concentrations on day 9 of treatment (33.4 ± 1.91 pg/mL) compared to the values measured on day 1 of trazodone administration (P = 0.001). Results: Serum β-endorphins measured on day 1 of trazodone application were significantly higher (72.31 ± 1.86 pg/mL x ± SEM) compared to baseline values (45.83 ± 3.77 pg/mL P = 0.001).